Iloperidone hydrochloride

Research use only, not for human use.

An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).

An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors; is used for the treatment of schizophrenia.Schizophrenia Approved

HP-873 hydrochloride

Endocrinology/Hormones

5-HT Receptor

5-HT Receptor

Neurological Disease

Schizophrenia

1299470-39-5

462.94

C24H28ClFN2O4

>98% (HPLC)

10 mM in DMSO

CC(C1=CC=C(OCCCN2CCC(C3=NOC4=CC(F)=CC=C34)CC2)C(OC)=C1)=O.[H]Cl

Ethanone, 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-, hydrochloride (1:1)

(-20℃)

With Ice Pack

≥ 2 years